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Research in the Prisinzano group is characterized by rigorous attention to the influence of chemical structure on biological activity. Our studies have predominantly focused on (a) the design and synthesis of novel biological probes for study of the mechanism of action of drugs of abuse and (b) the development of agents for the treatment and prevention of substance use disorder.

The lab is located on the third floor of the Lee Todd Jr. Building, which is situated on the Medical Campus in downtown Lexington, Kentucky. The College of Pharmacy takes great pride in providing an innovative education, conducting pioneering research, delivering cutting-edge clinical practice, and leading change to improve health.